WormBook

WormBook is a comprehensive, open-access collection of original, peer-reviewed chapters covering topics related to the biology of Caenorhabditis elegans (C. elegans). WormBook also includes WormMethods, an up-to-date collection of methods and protocols for C. elegans researchers.

WormBook Sections

Genetics and genomics

Developmental control

Signal transduction

Neurobiology and behavior

Evolution and ecology

WormMethods

Photo Credits

Molecular biology-Taken from Figure 3, Transcriptional regulation.

Cell biology-Taken from Figure 6, Cell division.

Sex determination-Taken from Figure 1, Male development.

The germ line-Taken from Figure 1, Introduction to the germ line.

Developmental control-Taken from Figure 5, Notch signaling in the C. elegans embryo.

Signal transduction-Taken from Figure 6, Signaling in the immune response.

Neurobiology and behavior-Taken from Figure 6, GABA. Adapted from Trends Neurosci 27, Schuske, K., Beg, A. A., and Jorgensen, E. M. The GABA nervous system in C. elegans. 407-414, Copyright (2004), with permission from Elsevier.

Evolution and ecology-Taken from Figure 1, A quick tour of nematode diversity and the backbone of nematode phylogeny.

WormMethods-Taken from Figure 3, Methods in cell biology.

All images, except where otherwise noted, are the expressed copyright of the respective authors. Images are from open-access articles distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Complete Table of Contents

Download All Chapters (380 MB .zip file)

How to Cite WormBook

News and Notes

WormBook chapters should be cited as in the following example:

Eisenmann, D. M., Wnt signaling (June 25, 2005), WormBook, ed. The C. elegans Research Community, WormBook, doi/10.1895/wormbook.1.7.1, http://www.wormbook.org.

The official publication date is the date the chapter is published online and can be found in the footer of each chapter. Chapters listed with preprint versions are citable with the words "in press" replacing the publication date and do not include a Digital Object Identifier (DOI).

EndNote: The complete set of WormBook citations are available for download into an EndNote bibliographic library. The reference set is available here. Please see the import instructions for details.

Mirror Site : Sanger Center (UK)

Please send us items you wish to appear in the News and Notes section via our Feedback page. Please also use this page to submit any general comments or suggestions regarding WormBook.

Oct 20, 2006

nGASP: nematode Genome Annotation Assessment Project
nGASP will be evaluating gene prediction software on the C. elegans genome. Please see the nGASP project page for details.

Oct 10, 2006

2007 C. elegans Meeting
The 16^th International C. elegans Meeting sponsored by the Genetics Society of America will be held June 27 - July 1, 2007 at UCLA.

Neurophysiological WormMethods Chapters Added
WormBook readers are invited to view the latest WormMethods chapters, Culture of embryonic C. elegans cells for electrophysiological and pharmacological analyses & Electrophysiological recordings from the neuromuscular junction of C. elegans

Oct 2, 2006

Fire and Mello awarded Nobel Prize for RNAi!

Congratulations to C. elegans researchers Andrew Fire and Craig Mello, the 2006 Nobel Laureates in Physiology or Medicine for their discovery of RNA interference. (more...)

Sep 7, 2006

Three New WormBook Chapters
Recent additions to WormBook include C. elegans network biology: a beginning, Oscheius tipulae, and Transcription mechanisms.

For a monthly email containing information about new additions to WormBook, please sign up at www.wormbook.org/announce.html.

Aug 31, 2006

Recent Additions to WormBook
WormBook has recently added "Heterologous expression of C. elegans ion channels in Xenopus oocytes" to the Neurophysiological methods section of WormMethods. Additionally, two new Pristionchus pacificus chapters have been published: "Pristionchus pacificus genomics: from genetics to genome sequence" in WormMethods and "Pristionchus pacificus" in the Genetics and genomics section of WormBook, launching our new subsection "Biology and genome of nematodes other than C. elegans".

July 31, 2006

New WormBook Chapters and WormMethods Sections
There were several new additions to WormBook's WormMethods section in July including "Behavior", "Immunohistochemistry", "Protocols for large scale in situ hybridization on C. elegans larvae", and a new methods section containing methods and protocols for nematode species other than C. elegans. This section currently has two chapters, "Pristionchus pacificus genetic protocols" and "Isolation of C. elegans and related nematodes", with more to be added soon. The Neurobiology and behavior section of WormBook has also expanded this month with the publication of "Male mating behavior".

All WormBook content, except where otherwise noted, is licensed under a Creative Commons Attribution License.

General information about WormBook on this page is copyrighted under the GNU Free Documentation License.